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課程名稱 |
生理遺傳學
PHYSIOLOGICAL GENETICS |
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開課學期 |
98-2 |
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授課對象 |
生物資源暨農學院 動物科學技術學研究所 |
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授課教師 |
丁詩同 |
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課號 |
AniSci8007 |
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課程識別碼 |
626 D0140 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期四6,7,8(13:20~16:20) |
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上課地點 |
加工105室 |
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備註 |
總人數上限：15人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/982phygene |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
1. Introduction-From gene to genetics
2. Online resources for genetics
3. Functional expression of a gene, transcriptional regulation and functional regulation
4. Techniques for physiological genetics research
5. Genes involved in animal growth-Molecular regulation of muscle growth
6. Polymorphism and single nucleotide polymorphism – Techniques and application
7. Genetic polymorphism and body composition
8. Growth selection and gene expression
9. Midterm
10. Functional existence of adipose tissue and adipokines
11. Molecular regulation of adipocyte differentiation and Molecular markers for obesity
12. Nutritional genomics research progresses
13. Proteomics research approaches for searching secretive proteins
14. Production of monoclonal antibody by transgenic animals
15. Genome-wide knockouts
16. Final report 1
17. Final report 2
18. Final report 3
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課程目標 |
這是一門講解、討論與影片演講並重的課
每週會有一個小時的報告、一個小時的影片演講與30分鐘的討論
所有的討論會使用英文，除非無法用中文表達時，可請求老師或同學幫忙翻譯
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課程要求 |
Lecture in English. Need to present talks, express opinion and discuss ideas in class. |
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預期每週課後學習時數 |
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Office Hours |
每週三 13:00~15:00 備註： Reports and presentations |
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指定閱讀 |
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參考書目 |
Primrose and Twyman, 2003. Principles of genome analysis and genomics. 3rd ed. Blackwell Publishing.
Thieman and Palladino, 2004. Introduction to biotechnology. Benjamin Cummings.Houdebine, L.M., 2003. Animal Transgenesis and cloning. Wiley.
Zhu et al., 2006. Production of human monoclonal antibody in eggs of chimeric chickens. Nature Biotechnology 23: 1159-1169.
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
Presentation |
30% |
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2. |
Report |
50% |
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3. |
Participation |
20% |
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週次 |
日期 |
單元主題 |
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第1週 |
2/25 |
Introduction
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第2週 |
3/04 |
Award travel
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第3週 |
3/11 |
Germ cells: my favorite cells張俊哲老師 |
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第4週 |
3/18 |
developmental biology, zebrafish李士傑老師 |
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第5週 |
3/25 |
endocrinology and vascular biology; cell culture李心予老師 |
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第6週 |
4/01 |
溫書假 |
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第7週 |
4/08 |
cancer cell biology and signaling; cell culture and mouse沈湯龍老師 |
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第8週 |
4/15 |
cell biology and autophage; yeast黃偉邦老師 |
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第9週 |
4/22 |
Topoisomerase and DNA damage; cell culture李財坤老師 |
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第10週 |
4/29 |
Insertional Mutagenesis and High Throughput Reverse Genetics陳佑宗老師 |
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第11週 |
5/06 |
Liver regeneration and stem cell research李宣書老師 |
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第12週 |
5/13 |
Polyunsaturated Fatty Acids Reduce Lipid Deposition by Increasing the Expression of Serum Amyloid Protein A丁詩同老師 |
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第13週 |
5/20 |
Epigenetics and developmental biology林邵品老師 |
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第14週 |
5/27 |
Stem cell and nanobiotechnology; cell culture周涵怡老師 |
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第15週 |
6/03 |
Final presentation1 |
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第16週 |
6/10 |
Final presentation2 |
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第17週 |
6/17 |
Final presentation3 |